Does Saffron Help You Sleep? What the Research Says

Cup of warm saffron milk, a dish of saffron threads and a candle on a bedside table

Does saffron help you sleep? Two small, well-designed trials suggest it may: adults with self-reported poor sleep who took a standardized saffron extract for 28 days rated their sleep quality better than people taking a placebo. The research is promising but early, it used one specific extract, and it measured how people felt about their sleep rather than lab sleep recordings. Here is what was studied, what saffron is, and how to think about it alongside the sleep habits that matter most.

Key takeaways

  • Two randomized trials found that a standardized saffron extract improved self-rated sleep quality over 28 days compared with placebo.
  • Both trials used one branded extract at small doses, so their results describe that extract.
  • Saffron was well tolerated in the studies, but large amounts of saffron are not safe.
  • Steady sleep habits do more for most people than any single supplement.

Does saffron help you sleep? What the studies found

Two randomized trials found that a standardized saffron extract improved self-rated sleep quality over 28 days compared with placebo. Both were run by the same Australian research group:

Study Who and what What changed
Lopresti et al., 2020 63 adults with self-reported poor sleep; 14 mg of a standardized saffron extract twice a day or placebo, for 28 days Greater improvement in sleep quality ratings than placebo; most of the change came in the first week
Lopresti et al., 2021 120 adults with unsatisfactory sleep; 14 mg or 28 mg of the same extract one hour before bed, or placebo, for 28 days Better sleep quality ratings and mood on waking; evening melatonin rose; several other measures did not differ from placebo

In both trials the extract was well tolerated, with no significant side effects reported. The researchers were careful about what they did not show: sleep was measured with diaries and questionnaires rather than overnight sleep recordings, the studies were short, and they called for longer trials with objective measures.

How might saffron affect sleep?

Nobody knows for sure. Saffron contains crocin and safranal, compounds that lab research links to the brain's signaling systems, and the 2021 trial found higher evening melatonin in the saffron groups. Melatonin is the hormone that rises in the evening to signal that it is time for sleep. That is a clue, not a full explanation.

What is saffron?

Saffron is the dried stigma of the saffron crocus (Crocus sativus), hand-picked from the center of each flower. Each flower gives only three stigmas, so it takes a very large number of flowers to make a small amount of spice, which is why saffron is known as the world's most expensive spice. Three compounds define it:

  • Crocin, a carotenoid pigment that gives saffron its deep golden color
  • Picrocrocin, responsible for its slightly bitter taste
  • Safranal, the main source of its aroma

A saffron extract concentrates these compounds so a capsule can deliver a consistent amount, which a pinch of kitchen saffron cannot.

Is saffron safe to take?

Clinical reviews describe saffron extracts as well tolerated at the small amounts used in research, typically well under 100 mg a day. Very large amounts, in the range of several grams, can be toxic. Keep to the label of any product you use and do not exceed the recommended dose.

  • Pregnancy and nursing: large amounts of saffron are considered unsafe during pregnancy; consult a physician before use.
  • Medications: if you take medication for mood, blood pressure, blood sugar or blood clotting, talk to your provider first.
  • Allergies: rare reactions to saffron have been reported.

Where saffron fits in an evening routine

Steady sleep habits do more for most people than any single supplement. Before adding anything, it is worth checking the basics:

  1. Keep a regular wake time, even on weekends; it anchors your body clock.
  2. Get daylight early in the day and dim the lights in the evening.
  3. Watch caffeine after midday and alcohol close to bedtime.
  4. Keep the bedroom cool, dark and quiet.
  5. Give yourself a wind-down of 30 to 60 minutes without screens.

If you are curious about how saffron compares with other evening options, our articles on magnesium vs. melatonin and waking up at 3am cover the most common choices.

When to talk to a professional about sleep

A supplement is not the right first step for every sleep problem. Book a visit with your doctor if any of these sound familiar:

  • Trouble falling or staying asleep most nights for more than a few weeks
  • Loud snoring, gasping or pauses in breathing that a partner has noticed
  • Daytime sleepiness that affects driving, work or your mood
  • Sleep changes that started with a new medication

These can have causes that need a proper look, and a good sleep evaluation is worth more than any capsule.

About our saffron extract

Our Bright Mood+™ is a one-ingredient saffron formula: 88.5 mg of saffron extract from the Crocus sativus flower in one veggie capsule, taken once a day, 20 to 30 minutes before a meal. It promotes cardiovascular health and helps protect the immune system.* It is a different extract from the one used in the sleep trials above, so those results describe their study product, not ours. Every batch is third-party tested for purity and potency in an NSF-certified, GMP-certified, FDA-registered U.S. facility; read more on our standards page.

Frequently asked questions about saffron and sleep

How long does saffron take to help with sleep?

In the 2020 trial, most of the change in sleep quality ratings appeared within the first seven days and held through day 28. The studies did not run longer than four weeks, so there is little data on long-term use.

When should you take saffron for sleep?

One trial gave the extract twice a day and the other gave it one hour before bed, and both reported benefits. If you use a saffron product, follow its own label directions.

Is saffron better than melatonin?

They have not been compared head to head. Melatonin is a hormone that mainly affects sleep timing, while saffron is a botanical studied for self-rated sleep quality. Talk with your provider about which, if either, suits you.

Can I just cook with saffron instead?

Cooking with saffron is a pleasure, but recipe amounts vary and are not standardized. The studies used measured, standardized extracts, so kitchen saffron is not a substitute for what was tested.

Does saffron make you drowsy the next day?

The trials did not report next-day drowsiness as a problem, and mood on waking improved in the 2021 study. Everyone responds differently, so see how you feel and stop if anything seems off.

Related reading from our Wellness Hub

Sources

Individual results vary.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


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