If you are wondering how to take a sleep supplement, start with the label: the right time, the right serving and the right glass of water matter more than any trick. For Restful Night+™, that means two capsules once a day, 20-30 minutes before bedtime, with an 8 fl oz glass of water. This guide walks through that routine step by step, what to skip on the nights you take it, and the label cautions you should read before your first serving.
Key takeaways
- Restful Night+ is taken as two capsules once a day, 20-30 minutes before bedtime, with an 8 fl oz glass of water.
- Each two-capsule serving lists 10 mg of melatonin, so it is a bedtime-only product, not a daytime calm aid.
- In plain words: do not combine Restful Night+ with alcohol or other sleep aids, and do not drive or operate machinery within 8 hours after use.
- A steady wind-down routine at the same time each night supports the formula; the capsule is one step, not the whole plan.
How to take a sleep supplement: the short answer
The best way to take any sleep supplement is the way its own label says. Labels differ on timing, serving size and food, and a formula built for bedtime is planned around the hour before you lie down. Restful Night+ is taken as two capsules once a day, 20-30 minutes before bedtime, with an 8 fl oz glass of water. That window gives you time to finish the evening, turn the lights down and get into bed while the formula is getting started.
Three habits make the routine work:
- Same time, most nights. Pick a bedtime you can keep on weeknights and weekends, and take your serving about 20-30 minutes before it.
- The full glass of water. The label asks for an 8 fl oz glass. There is no need to drink more than that right before bed.
- Only when you can stay in bed. Take it when you have a full night ahead, not before a late drive or an early shift.
Meet Restful Night+
Restful Night+ is our bedtime formula. It promotes restful sleep and relaxation and supports a calm, balanced mood.* Four ingredients are listed by amount, and a fourteen-ingredient sleep blend fills out the formula, which is where the "18 active sleep ingredients" on the front of the bottle comes from.

What is on the label
| Per serving (2 capsules) | Amount |
|---|---|
| Vitamin B-6 (Pyridoxine HCl) | 1.8 mg (106% DV) |
| Calcium (as Calcium Carbonate) | 17 mg (1% DV) |
| Magnesium (Magnesium Citrate) | 13 mg (3% DV) |
| Melatonin | 10 mg |
| Sleep Formula Proprietary Blend | 905 mg |
The blend lists L-tryptophan, lycium fruit, chamomile flower, lemon balm, passion flower, L-taurine, hops flower, St. John's Wort, GABA, Chinese skullcap root, L-theanine, ashwagandha root, inositol and 5-HTP from griffonia seed. Blend totals are on the label; the amounts inside each blend are not.
Each two-capsule serving lists 10 mg of melatonin, so it is a bedtime-only product, not a daytime calm aid. The bottle holds 60 vegetable capsules, which is a 30-day supply when used as directed. The formula is caffeine-free, gluten-free, vegan and sugar-free.
Why quality comes first
Every batch of Restful Night+ is third-party tested by an outside lab for purity and potency. It is manufactured in USA with globally sourced materials, in an NSF-certified, GMP-certified, FDA-registered U.S. facility. You can read how we test on our standards page. Every order is covered by our 60-day guarantee.
When should you take it, and does timing matter?
Melatonin is the hormone your body makes as evening falls, and a bedtime formula with melatonin is meant to be taken close to bedtime. The label window of 20-30 minutes keeps the serving tied to the moment you are ready to sleep. Taking it hours early, then staying up with screens and bright lights, works against the plan.
Research on melatonin itself is real but modest. A 2013 meta-analysis in PLoS One pooled 19 placebo-controlled trials with 1,683 adults and children who had been diagnosed with primary sleep disorders. Melatonin shortened the time to fall asleep by about 7 minutes and added about 8 minutes of total sleep, and overall sleep quality improved compared with placebo. The trials gave 0.1 to 5 mg of melatonin (one trial in children dosed by body weight). Within that range, longer trials and higher doses showed larger effects on those two measures. Restful Night+ lists 10 mg, which is above every dose tested here. The authors called the effects modest. That study looked at melatonin on its own, not at the Restful Night+ formula.
Should you take it with food?
The label does not ask for food. It asks for an 8 fl oz glass of water. Many people find a light evening and an earlier dinner make bedtime easier, but that is a habit choice, not a label rule.
What to skip on the nights you take Restful Night+
This is the part of the routine that matters most. The label is clear, and these lines are copied from it word for word:
- "Do not combine with alcohol or other sleep aids."
- "Do not drive or operate machinery within 8 hours after use."
- "Contains St. John's Wort and 5-HTP: consult your healthcare professional before use if you take any medication."
- "Do not exceed recommended dose."
- "Keep out of reach of children."
- "Do not use if safety seal is damaged or missing."
- "Store in a cool, dry place."
In plain words: do not combine Restful Night+ with alcohol or other sleep aids, and do not drive or operate machinery within 8 hours after use. "Other sleep aids" includes other melatonin products and our own nighttime formulas. Do not take 5-HTP+ with Restful Night+, because Restful Night+ already contains 5-HTP. Do not pair it with Night Balance+™ either. One sleep formula per night is the rule.
The National Center for Complementary and Integrative Health notes that, particularly at doses higher than what the body normally produces, there is not yet enough information on side effects for a clear picture of overall safety. Short-term use appears to be safe for most people, but information on long-term safety is lacking. Mild side effects reported in studies include headache, dizziness, nausea and sleepiness. NCCIH also says people taking medicine should talk with their health care provider first, and people with epilepsy or on blood thinners need medical supervision when taking melatonin.
A simple bedtime routine around your serving
A steady wind-down routine at the same time each night supports the formula; the capsule is one step, not the whole plan. A supplement works best inside a routine that already points toward sleep. Here is an easy order to follow:
- 60 minutes before bed: dim the lights, put the phone on the charger outside arm's reach, and finish anything that needs your attention.
- 30 minutes before bed: take two capsules of Restful Night+ with an 8 fl oz glass of water.
- 20 minutes before bed: a warm shower, a few pages of a paper book or a slow stretch.
- Bedtime: a cool, dark, quiet room, and the same wake-up time the next morning.
The National Heart, Lung, and Blood Institute lists the same basics: a regular sleep schedule, a relaxing routine before bed, a sleep space that is dark and cool, and limits on alcohol and caffeine late in the day. If you want more ideas for the hour before bed, our guide to building an evening wind-down ritual has a full plan.
Who should check with a professional first?
The label says: "Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement." Because the formula contains St. John's Wort and 5-HTP, anyone who takes a prescription or over-the-counter medicine should ask a healthcare professional before the first serving. Bring the bottle, or a photo of the Supplement Facts panel, so they can see every ingredient.
Frequently asked questions about how to take a sleep supplement
How long before bed should I take Restful Night+?
The label says 20-30 minutes before bedtime. Take two capsules with an 8 fl oz glass of water, then start winding down so you are in bed when that window ends.
Can I take one capsule instead of two?
The serving on the label is two capsules once a day. If you are unsure whether the full serving is right for you, ask your healthcare professional before you start, and never take more than the label serving.
Can I have a glass of wine with Restful Night+?
No. The label says "Do not combine with alcohol or other sleep aids." Save Restful Night+ for nights without alcohol.
Can I take it with 5-HTP+ or another melatonin product?
No. Restful Night+ already contains 5-HTP and 10 mg of melatonin, and the label says not to combine it with other sleep aids. Choose one sleep formula for the night.
Is Restful Night+ caffeine-free?
Yes. The formula is caffeine-free and comes in a vegetable capsule. It is also gluten-free, vegan and sugar-free.
Related reading from our Wellness Hub
- Sleep Supplement Ingredients Explained: Inside Restful Night+
- Melatonin and Sleep: How Much, When, and Cautions
- The Wind-Down Ritual: How to Build an Evening Routine for Deeper Sleep
Sources
- National Center for Complementary and Integrative Health. Melatonin: What You Need To Know. Last updated May 2024.
- Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013.
- National Heart, Lung, and Blood Institute. Healthy Sleep Habits. Last updated March 24, 2022.
Individual results vary.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



