The simplest way to take myo-inositol is the same way, every day: follow the serving on your label, pair it with a meal you never skip, and give it about three months before you judge it, the length of the 2019 Nordio trial cited below. Myo-inositol works on slow processes such as hormone signaling and how cells respond to insulin. With Myo Inositol+™, you take two capsules once a day, 20-30 minutes before a meal.
Key takeaways
- Myo-inositol works on slow processes such as hormone signaling and how cells respond to insulin.
- Take two capsules once a day, 20-30 minutes before a meal, as the label directs.
- Each two-capsule serving provides 1,000 mg of myo-inositol and 25 mg of D-chiro inositol.
- The 2019 Nordio trial, in women with PCOS taking about four times one serving, ran three months; give it at least that long.
- Inositol is generally well tolerated; a 2011 review of trials using 4 to 30 g of myo-inositol a day, all above the 1,000 mg in one serving, found mild digestive side effects mainly at 12 g a day or more, and its authors noted that safety information was still scarce.
- The Myo Inositol+ label says not to exceed the recommended dose, and that pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
What is myo-inositol?
Inositol is a vitamin-like sugar alcohol found in every cell of the body. It is sometimes called "vitamin B8," but it is not a true vitamin, because the body can make it from glucose. Myo-inositol is the most common of its nine forms. Inside cells it acts as a messenger, helping relay signals from hormones such as insulin and follicle-stimulating hormone (FSH). D-chiro inositol is a second form that the body makes from myo-inositol, and the two are found together in tissues in different ratios.
Supplements pair them because research has looked at both. A 2019 trial by Nordio and colleagues in women with polycystic ovary syndrome (PCOS) compared seven ratios, including 40:1, the ratio found in blood plasma. We explain the background in Myo-inositol vs. D-chiro-inositol: what the 40:1 ratio means.
How to take myo-inositol with Myo Inositol+
Myo Inositol+ is a women's health and wellness formula that supports hormonal balance and reproductive health in women, supports healthy ovarian function, and helps support healthy glucose metabolism.* There is no blend: both amounts are printed on the label.
| Serving | 2 capsules |
| Per serving | Myo-inositol 1,000 mg; D-chiro inositol (Caronositol®) 25 mg |
| Direction | Two capsules once a day, 20-30 minutes before a meal |
| Supply | 60 capsules = 30 days |
| Diet notes | Vegan, gluten-free, non-GMO, sugar-free, caffeine-free |
Each two-capsule serving provides 1,000 mg of myo-inositol and 25 mg of D-chiro inositol. The label direction is two capsules once a day, 20-30 minutes before a meal. Take both capsules together at the same time each day.
Morning or evening?
The label sets no required time of day. Many people choose breakfast because it is the easiest meal to repeat, while others prefer dinner. Inositol does not contain caffeine, so an evening serving will not keep you awake. Pick the slot you will remember on busy days, because skipped servings matter more than the clock.
With or without food?
The direction is 20-30 minutes before a meal. Having food on the way soon after is also a practical way to keep the routine consistent.
How long does myo-inositol take to work?
The 2019 Nordio trial, in women with PCOS taking 2 g of inositols twice a day (4 g a day, about four times one Myo Inositol+ serving), ran for three months, so a fair trial of your own routine is at least that long. Some people notice changes sooner, and some need longer; individual results depend on diet, sleep, activity and the reason you are taking it. Because hormone cycles take weeks to play out, judging myo-inositol after a week or two tells you very little.
- Month 1: build the habit and note how your digestion feels.
- Month 2: keep a short weekly log of cycle timing and how you feel overall.
- Month 3: compare your notes with week one and review them with your healthcare provider.
Food first, then a supplement
Inositol is in many everyday foods. Fruits (especially citrus and cantaloupe), beans, lentils, whole grains, nuts and seeds all contain it, often in the form of phytic acid that the gut breaks down. A varied diet supplies a modest amount each day. Supplements exist because a capsule delivers a known, measured amount of each form every day.
A good routine uses both: build meals around plants, protein and fiber, and use a supplement as a steady, measurable layer on top. If you track what you eat, there is no need to count inositol from food; it simply supports the same goal.
Is myo-inositol safe to take every day?
Inositol is generally well tolerated. A 2011 safety review by Carlomagno and Unfer looked at clinical trials that used 4 to 30 g of myo-inositol a day and found mild digestive side effects such as nausea, gas and diarrhea mainly at 12 g a day or more, and the authors noted that information on myo-inositol safety was still scarce. A Myo Inositol+ serving has 1,000 mg of myo-inositol, lower than every dose in those trials. The label warning reads: "Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place." If you take medicine that affects blood sugar, ask your provider first, since inositol is studied for its role in glucose metabolism.
Why the label matters with inositol
Inositol is an ingredient where cheap products cut corners, for example by leaving the D-chiro amount off the label. Myo Inositol+ lists both forms with their amounts, and every batch is third-party tested for purity and potency by an outside lab. It is manufactured in USA with globally sourced materials in an NSF-certified, GMP-certified, FDA-registered facility. Read more on our standards page. It is backed by our 60-day guarantee.
Frequently asked questions about myo-inositol
Can I split the two capsules into a morning and an evening dose?
The label direction is two capsules once a day, taken together. Following the label keeps the trial consistent. If you have a reason to split it, discuss it with your healthcare provider first.
Does myo-inositol cause weight gain?
No research we are aware of links myo-inositol to weight gain. Each serving is sugar-free and contains essentially no calories. Inositol is studied for its role in how the body handles glucose, not as a weight product.
Can I take myo-inositol with a multivitamin?
Generally yes. Inositol is not in most multivitamins, but some B-complex formulas include it (Energy+™ has 150 mg per serving), so add it up. The two labels give different directions: Myo Inositol+ is two capsules once a day, 20-30 minutes before a meal, and Energy+ is two capsules once daily with food and an 8 fl oz glass of water, so take each one as its own label directs. The Energy+ and Myo Inositol+ labels carry the same printed warning: do not exceed recommended dose; pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement; keep out of reach of children; do not use if safety seal is damaged or missing; and store in a cool, dry place. Check the label of anything else you take so you know your total inositol intake, and ask your provider if you are unsure. If you take Energy+ with a multivitamin, add up the vitamins too. One Energy+ serving gives 700 mcg of folic acid, 30 mg of vitamin B6, 20 mg of niacin, 150 mg of vitamin C and 100 mg of choline. The NIH Office of Dietary Supplements lists these adult upper limits (ULs): 1,000 mcg of folate from supplements or fortified foods, 35 mg of niacin from supplements, and 100 mg of vitamin B6, 2,000 mg of vitamin C and 3,500 mg of choline from food and supplements together. Its vitamin B6 fact sheet also notes that in 2023 the European Food Safety Authority (EFSA) "set an upper limit for vitamin B6 of 12 mg/day for all adults"; one Energy+ serving gives 30 mg, above that EFSA limit. The same ODS fact sheets list medicine interactions for these vitamins: folate with methotrexate, antiepileptic drugs such as phenytoin, carbamazepine and valproate, and sulfasalazine; vitamin B6 with cycloserine, antiepileptic drugs and theophylline; niacin with the tuberculosis drugs isoniazid and pyrazinamide and, in large doses of nicotinic acid, with diabetes medicines; and vitamin C with chemotherapy, radiation therapy and statins. ODS advises anyone who takes these medicines regularly to discuss these vitamins with their health care provider, and anyone taking methotrexate for cancer, or having chemotherapy or radiation, to ask their oncologist first. The sheets also note that large amounts of folate may worsen the anemia and cognitive symptoms of vitamin B12 deficiency, that high doses of vitamin C could worsen iron overload in people with hereditary hemochromatosis, and that high vitamin C intakes could add to kidney stone formation, especially in people with kidney disorders.
What does Caronositol® mean on the label?
Caronositol® is a branded form of D-chiro inositol made from carob. Myo Inositol+ provides 25 mg of it per two-capsule serving, alongside 1,000 mg of myo-inositol.
What if I miss a day?
Take your next serving at the usual time and do not double up. One missed day will not undo your progress, but frequent gaps make it hard to judge how the routine is working.
Related reading from our Wellness Hub
- Inositol for Hormonal Balance: Meet Myo Inositol+ (40:1)
- Myo-Inositol vs. D-Chiro-Inositol: What the 40:1 Ratio Means
- Is Inositol a B Vitamin? What It Is and Where It's Found
Sources
- Nordio M, et al. The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios. Eur Rev Med Pharmacol Sci, 2019
- Carlomagno G, Unfer V. Inositol safety: clinical evidences. Eur Rev Med Pharmacol Sci, 2011
- NIH Office of Dietary Supplements: Folate - Health Professional Fact Sheet, updated 2022
- NIH Office of Dietary Supplements: Vitamin B6 - Health Professional Fact Sheet, updated 2023
- NIH Office of Dietary Supplements: Niacin - Health Professional Fact Sheet, updated 2022
- NIH Office of Dietary Supplements: Vitamin C - Health Professional Fact Sheet, updated 2025
- NIH Office of Dietary Supplements: Choline - Health Professional Fact Sheet, updated 2022
Individual results vary.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
