Urinary Comfort+™ is a D-mannose and cranberry supplement with two supporting botanicals, and its label hides nothing. Each two-capsule serving holds 1,000 mg of D-mannose, 150 mg of cranberry juice powder, 100 mg of hibiscus flower extract and 100 mg of dandelion root extract: 1,350 mg in total, with no proprietary blend. Below, each ingredient in turn: what it is, why it is there, and what the research does and does not show.
Key takeaways
- Each two-capsule serving of Urinary Comfort+ holds 1,000 mg of D-mannose, 150 mg of cranberry juice powder, 100 mg of hibiscus extract and 100 mg of dandelion extract.
- Take two veggie capsules once a day, as the label directs. Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
- There is no proprietary blend: all four amounts are printed separately on the label.
- D-mannose is a simple sugar found naturally in fruits such as cranberries.
- Urinary Comfort+ supports urinary tract health and helps maintain urinary comfort; it is not a medicine and not a substitute for medical care.
The four ingredients in this D-mannose and cranberry supplement
The table gives each ingredient, its source, the amount in one two-capsule serving and why it is in the formula.
| Ingredient | Source | Per 2-capsule serving | Why it is in the formula |
|---|---|---|---|
| D-mannose | A simple sugar | 1,000 mg | The lead ingredient for urinary tract support |
| Cranberry juice powder | Vaccinium macrocarpon, fruit | 150 mg | Cranberry's own plant compounds |
| Hibiscus extract | Hibiscus sabdariffa, flower | 100 mg | Polyphenols and anthocyanins |
| Dandelion extract | Taraxacum officinale, root | 100 mg | Traditional use for fluid balance |
Together they make a formula designed to support urinary tract health, promote a healthy bladder environment, encourage natural detoxification and fluid balance, and provide antioxidants for whole-body wellness.*
D-mannose: the lead ingredient
D-mannose is a simple sugar found naturally in fruits such as cranberries. It is a close relative of glucose, but the body handles it differently: a 2021 review in Frontiers in Pharmacology describes D-mannose as absorbed but not metabolized the way ordinary sugars are, so much of it passes into the urine. The proposed idea is that it acts as a decoy there, giving certain bacteria something to bind to other than the bladder lining.
Here is the honest research picture. Most D-mannose studies were done in people with recurring urinary infections. A 2022 Cochrane review found little to no evidence to support or refute D-mannose, mainly because good trials were scarce, and a large 2024 randomized trial in 598 women with recurrent urinary infections in UK primary care, using 2 g a day of D-mannose powder for six months, found no significant difference from placebo in its main outcome; its authors concluded D-mannose should not be recommended for prevention in that group. Those were studies of a medical question, not tests of our formula, and our serving has 1,000 mg of D-mannose, half that trial's daily dose. Our comparison of D-mannose vs. cranberry goes into more detail.
Cranberry juice powder
Cranberry (Vaccinium macrocarpon) is the tart North American fruit, and juice powder is the juice dried to a powder. According to NCCIH, cranberry's proanthocyanidins (PACs) are thought to keep bacteria from sticking to the bladder wall, and processing cranberries into tablets or capsules can lower PAC levels. The Urinary Comfort+ label lists cranberry juice powder by weight and does not state a PAC amount, so we describe it as what it is: a supporting cranberry ingredient. For the different cranberry forms, see cranberry pills vs. cranberry juice.
NCCIH advises anyone taking warfarin or other medicines to talk with a health care provider before using cranberry.
Hibiscus extract
The hibiscus here is Hibiscus sabdariffa, or roselle, the plant behind the tart red drink known as sour tea or agua de jamaica. It is rich in organic acids, polyphenols and anthocyanins, the pigments that give it its deep red color, and it contributes to the formula's antioxidant profile.* Most human research on hibiscus has looked at the tea and blood pressure, which is why anyone taking blood pressure medicine should mention it to their prescriber.
Dandelion extract
Dandelion (Taraxacum officinale) has a long traditional use for fluid balance. Urinary Comfort+ uses the root. NCCIH is candid that very little is known about dandelion's effects on human health, and it lists possible interactions with diabetes medicines, blood thinners and water pills. People allergic to plants in the daisy family, such as ragweed, should also take care. Our article on hibiscus and dandelion in urinary supplements covers both botanicals in depth.
Other ingredients and quality
- Hypromellose: the vegetable capsule shell.
- Silicon dioxide: a common flow agent that keeps powders from clumping.
Every batch is third-party tested for purity and potency, and the formula is made in an NSF-certified, GMP-certified, FDA-registered U.S. facility. See our standards for how testing works.
How to take Urinary Comfort+
The label direction is two veggie capsules once a day, 20 to 30 minutes before a meal with an 8 fl oz glass of water, or as directed by your healthcare professional. Do not exceed the recommended dose. A bottle holds 60 capsules, 30 servings, or about 30 days. Our guide on when to take D-mannose turns that into a routine.
Who should check with a clinician first
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Check first, too, if you take warfarin or another blood thinner, diabetes medicine, blood pressure medicine or a water pill.
Urinary Comfort+ supports urinary tract health and helps maintain urinary comfort; it is not a medicine and not a substitute for medical care. Burning when you urinate, cloudy or bloody urine, fever, or pain in your back or side are reasons to contact a health care professional promptly.
Frequently asked questions about this D-mannose and cranberry supplement
How much D-mannose is in Urinary Comfort+?
Each two-capsule serving of Urinary Comfort+ contains 1,000 mg of D-mannose, alongside 150 mg of cranberry juice powder, 100 mg of hibiscus extract and 100 mg of dandelion extract. Do not exceed the recommended dose of two capsules a day. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Does Urinary Comfort+ contain a proprietary blend?
No. All four ingredients are listed separately with their own amounts, 1,350 mg in total per serving.
How is this different from a plain D-mannose supplement?
A plain D-mannose product contains D-mannose alone. Urinary Comfort+ pairs D-mannose with cranberry juice powder and two supporting botanicals, hibiscus and dandelion, in one daily serving.
Can I drink cranberry juice while taking Urinary Comfort+?
A glass of cranberry juice is a common drink, but sweetened juice cocktails add sugar and it all adds to your cranberry intake. If you take warfarin or other medicines, talk with your healthcare provider first. Do not exceed the recommended dose of Urinary Comfort+. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
How long does a bottle last?
A bottle of Urinary Comfort+ holds 60 veggie capsules. At the label's two capsules once a day, that is 30 servings, or about 30 days. Do not exceed recommended dose; pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Related reading from our Wellness Hub
- D-Mannose vs. Cranberry: How They Differ for Urinary Wellness
- Hibiscus and Dandelion in Urinary Supplements: What They Add
- When to Take D-Mannose: How to Take Urinary Comfort+ With Water
- Cranberry Pills vs. Cranberry Juice: Which Fits a Daily Routine?
Sources
- Scaglione F, et al. Considerations on D-mannose Mechanism of Action and Consequent Classification of Marketed Healthcare Products. Frontiers in Pharmacology, 2021 (PubMed)
- Cooper TE, et al. D-mannose for preventing and treating urinary tract infections. Cochrane Database of Systematic Reviews, 2022 (PubMed)
- Hayward G, et al. D-Mannose for Prevention of Recurrent Urinary Tract Infection Among Women: A Randomized Clinical Trial. JAMA Internal Medicine, 2024 (PubMed)
- NCCIH - Cranberry: usefulness and safety, updated November 2024
- NCCIH - Dandelion: usefulness and safety, updated November 2024
- Serban C, et al. Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials. J Hypertens, 2015 (PubMed)
Individual results vary.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
