Immune+ Ingredients: What Each of the Ten Actives Does

Immune+ ingredients, in short: ten actives in every 2-capsule serving - European elderberry extract 300 mg, vitamin C 180 mg, vitamin E 20 mg, vitamin B6 3.4 mg, zinc 16 mg, echinacea 200 mg, garlic 100 mg, turmeric 100 mg, L-glutamine 200 mg and Lactobacillus acidophilus at 4.8 Billion CFU. Every amount is printed on the label, with no proprietary blend. Below, we walk through each ingredient: what it is, what it does in the body, what research says and the safety notes worth knowing.

The full Immune+ label at a glance

Immune+ contains ten active ingredients, and every amount is printed on the label. Here they are per 2-capsule serving, with the plain-English job of each:

Ingredient	Amount	In one line
European elderberry extract (fruit)	300 mg	Dark berry rich in anthocyanin pigments
Vitamin C (ascorbic acid)	180 mg (200% DV)	Antioxidant vitamin used by immune cells
Vitamin E (DL-alpha tocopherol acetate)	20 mg (133% DV)	Fat-soluble antioxidant for cell membranes
Vitamin B6 (pyridoxine HCl)	3.4 mg (200% DV)	Helps the body use protein and make immune cells
Zinc (zinc oxide)	16 mg (146% DV)	Mineral that immune cells need to develop
Echinacea purpurea powder (aerial)	200 mg	Traditional coneflower botanical
Garlic powder (bulb)	100 mg	Culinary herb with sulfur compounds
Turmeric, 95% curcuminoids (root)	100 mg	Golden root standardized for curcuminoids
L-glutamine HCl	200 mg	Amino acid used as fuel by gut and immune cells
Lactobacillus acidophilus	4.8 Billion CFU	Lactic acid probiotic bacterium

The only other ingredient is hypromellose, the plant-based material of the veggie capsule.

The hero botanical: European elderberry

Elderberry extract, 300 mg. Elderberry comes from the fruit of Sambucus nigra, the European black elder tree. The berry is naturally rich in anthocyanins, the deep purple pigments also found in blueberries and blackcurrants. People have cooked elderberries into syrups and teas for centuries. NCCIH notes that a small number of studies have evaluated elderberry for colds, flu and other upper respiratory infections, and calls the research preliminary. Supplements use processed fruit extract, because raw berries, leaves and stems should never be eaten. Our elderberry vs. echinacea guide covers both herbs in depth.

The four immune nutrients

The four nutrients - vitamins C, E and B6 and zinc - each provide at least 133% of the Daily Value. The NIH Office of Dietary Supplements lists all four among the nutrients involved in normal immune function.

Vitamin C, 180 mg. A water-soluble antioxidant your body cannot make. White blood cells collect it at high levels, and it also helps make collagen and absorb plant iron. Absorption is efficient at everyday amounts and drops at very high doses, so steady intake beats megadosing.

Vitamin E, 20 mg. A fat-soluble antioxidant that helps protect the fatty membranes around every cell, including immune cells. Our formula uses DL-alpha tocopherol acetate, a stable form of vitamin E that is common in supplements. The NIH Office of Dietary Supplements lists 15 mg a day for adults (19 mg while breastfeeding).

Vitamin B6, 3.4 mg. Per the NIH Office of Dietary Supplements, vitamin B6 is involved in more than 100 enzyme reactions, mostly in protein metabolism. The body also needs it to make immune cells and the signalling molecules they use. The NIH Office of Dietary Supplements lists 1.3 to 1.7 mg a day for adults (1.9 mg in pregnancy, 2.0 mg while breastfeeding) and an adult upper limit of 100 mg a day from food and supplements. Immune+ gives 3.4 mg, so if you take a B-complex as well, add up the B6.

Zinc, 16 mg. A trace mineral that, per the NIH Office of Dietary Supplements, about 100 enzymes need in order to work. Immune cells need zinc to develop and signal properly, and the body has no special store of it. Zinc oxide is a concentrated, stable form. Immune+ gives 16 mg, and the NIH Office of Dietary Supplements lists an adult upper limit of 40 mg a day from food and supplements, so add up zinc from any other supplement you take. Our zinc guide explains forms and food sources, and our article on vitamin C and zinc together compares the two.

The three supporting botanicals

The botanicals are elderberry, echinacea, garlic and turmeric, with elderberry as the lead ingredient. The other three play supporting roles in modest amounts.

Echinacea purpurea, 200 mg. The purple coneflower, used here as a powder of the aerial parts (flowers, leaves and stems). The NIH Office of Dietary Supplements notes that most echinacea studies have looked at the common cold and other upper respiratory illnesses, that supplements often mix species and plant parts, and that results for colds have been mixed. Echinacea is in the daisy family, and some people are allergic to it.

Garlic, 100 mg. Powdered garlic bulb. Garlic is best known for its sulfur compounds, such as allicin, which forms when garlic is crushed. NCCIH notes that very little research has looked at garlic supplements for immune support specifically, so we include it as a traditional supporting herb. NCCIH says garlic supplements may increase the risk of bleeding.

Turmeric 95% curcuminoids, 100 mg. An extract of turmeric root standardized so that 95% of it is curcuminoids, the compounds NCCIH says turmeric's health activities are commonly attributed to. Curcuminoids act as antioxidants in lab studies. Our turmeric vs. curcumin guide explains what the percentage on a label means.

The gut-focused pair

L-glutamine and Lactobacillus acidophilus reflect the close link between the gut and the immune system. A large share of immune tissue sits along the digestive tract, just beneath the gut lining.

L-glutamine HCl, 200 mg. Glutamine is the most abundant amino acid in the body, per a 2018 review in Nutrients by Cruzat and colleagues. The body makes its own, and cells lining the gut, along with many immune cells, use it as a main fuel, especially during physical stress.

Lactobacillus acidophilus, 4.8 Billion CFU. A lactic acid bacterium that lives naturally in the human gut and has long been used in fermented foods. CFU stands for colony-forming units, the number of live bacteria. Probiotic effects depend on the strain and the amount, so this is a supporting ingredient, not a substitute for a dedicated probiotic. Read more in our article on the gut-immune connection.

What Immune+ supports

Put together, Immune+ supports a healthy immune system, helps maintain antioxidant defenses and supports seasonal wellness.* It also helps maintain overall respiratory health and provides daily nutrient support.* The studies mentioned above used their own preparations and amounts, which are not the amounts in our formula, so we keep our claims to the label.

The formula is vegan, vegetarian, gluten free, non-GMO, sugar free, lactose free, free of the top 9 allergens and corn free. Every batch is third-party tested by an outside lab for purity and potency, and it is manufactured in USA with globally sourced materials, in an NSF-certified, GMP-certified, FDA-registered U.S. facility. Read how we test on our Our Standards page.

How to take Immune+ and who should check first

The suggested use is two veggie capsules once a day. For best results, take them 20 to 30 minutes before a meal with an 8 fl oz glass of water, or as directed by your healthcare professional. A bottle holds 60 capsules, which is a 30-day supply when used as directed. NCCIH says conventional turmeric (not made for higher absorption) is likely safe in the recommended amounts for up to 2 or 3 months, so ask your healthcare professional before using Immune+ for longer than that.

The label warning reads: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.

The cited sources give stronger pregnancy cautions for four of the ingredients. The NIH Office of Dietary Supplements (ODS) says the safety of elderberry and of echinacea during pregnancy is not known, so experts recommend against both supplements during pregnancy. NCCIH says the use of turmeric supplements during pregnancy may be unsafe, and that garlic may not be safe during pregnancy or while breastfeeding in amounts greater than those found in foods.

The same sources name these medicine and health-condition cautions. If you take any medicine, NCCIH advises talking with your health care provider before using herbal products.

• Garlic: NCCIH says to tell your health care providers you take it, especially before surgery or if you take anticoagulants, aspirin or other medicines that affect bleeding. ODS adds that garlic might interact with warfarin and similar medicines (case reports are inconclusive) and with blood pressure medicines.
• Echinacea: ODS says it might lower levels of some drugs broken down by cytochrome P450 enzymes and might reduce the effect of immunosuppressants. It can cause allergic reactions in rare cases, and isolated reports have linked it to liver injury, though a contaminant or the product's preparation may have been the cause.
• Elderberry: ODS says it might affect insulin and glucose metabolism, so experts advise people with diabetes to use it with caution, and it might reduce the effect of immunosuppressants.
• Turmeric: NCCIH says liver damage has been reported in some people taking curcumin products made for higher absorption. If you notice signs such as fatigue, nausea, poor appetite, dark urine or jaundice, NCCIH says to stop turmeric or curcumin products immediately (Immune+ contains turmeric) and talk with your health care provider.
• Vitamins C and E: ODS says both might reduce the effectiveness of chemotherapy and radiation therapy. Vitamin C might increase levothyroxine absorption when taken at the same time, people with hemochromatosis should be cautious with vitamin C above the RDA (Immune+ gives 180 mg, above the adult RDA), and high intakes might cause false readings on some blood glucose meters. Vitamin E might interact with anticoagulant and antiplatelet medicines, and the ODS vitamin E sheet adds simvastatin and niacin.
• Zinc: ODS says zinc can reduce the absorption of some antibiotics and penicillamine, and that thiazide diuretics and certain antibiotics can reduce zinc absorption.
• Vitamin B6: the ODS vitamin B6 sheet says B6 can interact with certain medicines and that some, such as cycloserine, some antiepileptic drugs and theophylline, affect B6 levels; people who take them regularly should discuss their B6 status with their health care provider.
• Lactobacillus acidophilus: ODS says that in a few cases, mainly in people who were severely ill or immunocompromised, probiotics were linked to serious infections, and that antibiotic and antifungal medicines might make some probiotics less effective.

Frequently asked questions about Immune+ ingredients

What are the ingredients in Immune+?

Immune+ contains European elderberry extract, vitamin C, vitamin E, vitamin B6, zinc, Echinacea purpurea, garlic, turmeric with 95% curcuminoids, L-glutamine and Lactobacillus acidophilus. The capsule is made of hypromellose, a plant-based material.

Does Immune+ have a proprietary blend?

No. Every one of the ten ingredients is listed with its exact amount per 2-capsule serving, so you can compare it with any other supplement you take.

How much elderberry is in Immune+?

Each 2-capsule serving of Immune+ contains 300 mg of European elderberry extract from the fruit of Sambucus nigra. It is the largest single ingredient by weight in the formula.

Is Immune+ safe to take with a multivitamin?

Often yes, but add up both labels. Each 2-capsule serving of Immune+ gives 180 mg vitamin C, 20 mg vitamin E, 3.4 mg vitamin B6 and 16 mg zinc. The NIH Office of Dietary Supplements lists adult upper limits of 2,000 mg vitamin C, 100 mg vitamin B6 and 40 mg zinc a day from food and supplements, and 1,000 mg vitamin E a day from supplements. The Immune+ label says: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. In pregnancy, NIH sources go further: experts advise against elderberry and echinacea supplements, NCCIH calls turmeric supplements possibly unsafe, and garlic above food amounts may not be safe while pregnant or breastfeeding. Ask your healthcare professional if you are unsure.

Does Immune+ contain any common allergens?

Immune+ is listed as free of the top 9 allergens, as well as gluten free, lactose free and corn free. People allergic to daisy-family plants should check with a healthcare professional because of the echinacea.

Related reading from our Wellness Hub

• Daily Immune Support Supplement: Meet Immune+
• How to Take Immune+: Best Time, Meals and a Daily Routine
• Third-Party Tested, Every Batch: Here’s the Receipt

Sources

• NIH Office of Dietary Supplements - Dietary Supplements for Immune Function and Infectious Diseases, updated March 10, 2025
• NIH Office of Dietary Supplements - Vitamin E: Fact Sheet for Health Professionals, updated October 19, 2026
• NIH Office of Dietary Supplements - Vitamin B6: Fact Sheet for Health Professionals, updated June 16, 2023
• NCCIH - European Elder (Elderberry), updated November 2024
• NCCIH - Garlic, updated February 2025
• NCCIH - Turmeric, updated April 2025
• Cruzat V, et al. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018.

Individual results vary.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.